Anti-Muellerian hormone (AMH)

About Anti-Muellerian hormone

Anti-Muellerian hormone (AMH) is a protein from Homo sapiens identified by UniProt accession P03971, 560 residues long. MolForge cross-references it against 0 known binders and 549 disease associations.

Target properties

Protein name	Anti-Muellerian hormone
UniProt accession	P03971
Gene	AMH
Organism	Homo sapiens
Length	560 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (549)

Diseases linked to this target (Open Targets).

persistent Mullerian duct syndrome · score 0.74
Persistent Müllerian duct syndrome · score 0.74
pulse pressure measurement · score 0.33
genetic non-acquired premature ovarian failure · score 0.26
genetic disorder · score 0.19
polycystic ovary syndrome · score 0.13
body mass index · score 0.12
mean corpuscular volume · score 0.11
endometriosis · score 0.11
insulin resistance · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P03971-F1	alphafold	PREDICTED	68.63	—

Amino-acid sequence (560 residues)

MRDLPLTSLA LVLSALGALL GTEALRAEEP AVGTSGLIFR EDLDWPPGSP QEPLCLVALG GDSNGSSSPL RVVGALSAYE QAFLGAVQRA RWGPRDLATF GVCNTGDRQA ALPSLRRLGA WLRDPGGQRL VVLHLEEVTW EPTPSLRFQE PPPGGAGPPE LALLVLYPGP GPEVTVTRAG LPGAQSLCPS RDTRYLVLAV DRPAGAWRGS GLALTLQPRG EDSRLSTARL QALLFGDDHR CFTRMTPALL LLPRSEPAPL PAHGQLDTVP FPPPRPSAEL EESPPSADPF LETLTRLVRA LRVPPARASA PRLALDPDAL AGFPQGLVNL SDPAALERLL DGEEPLLLLL RPTAATTGDP APLHDPTSAP WATALARRVA AELQAAAAEL RSLPGLPPAT APLLARLLAL CPGGPGGLGD PLRALLLLKA LQGLRVEWRG RDPRGPGRAQ RSAGATAADG PCALRELSVD LRAERSVLIP ETYQANNCQG VCGWPQSDRN PRYGNHVVLL LKMQVRGAAL ARPPCCVPTA YAGKLLISLS EERISAHHVP NMVATECGCR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards