T cell receptor gamma variable 3 (TRGV3)

About T cell receptor gamma variable 3

T cell receptor gamma variable 3 (TRGV3) is a protein from Homo sapiens identified by UniProt accession P03979, 118 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	T cell receptor gamma variable 3
UniProt accession	P03979
Gene	TRGV3
Organism	Homo sapiens
Length	118 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

chronic kidney disease · score 0.04
COVID-19 · score 0.01
Sepsis · score 0.00
ulcerative colitis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P03979-F1	alphafold	PREDICTED	87.16	—

Amino-acid sequence (118 residues)

MRWALLVLLA FLSPASQKSS NLEGRTKSVT RQTGSSAEIT CDLTVTNTFY IHWYLHQEGK APQRLLYYDV STARDVLESG LSPGKYYTHT PRRWSWILRL QNLIENDSGV YYCATWDR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards