Cystatin-B (CSTB)

About Cystatin-B

Cystatin-B (CSTB) is a protein from Homo sapiens identified by UniProt accession P04080, 98 residues long. MolForge cross-references it against 0 known binders and 366 disease associations.

Target properties

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Disease associations (366)

Diseases linked to this target (Open Targets).

• Unverricht-Lundborg syndrome · score 0.80
• Unverricht-Lundborg disease · score 0.74
• Progressive myoclonic epilepsy · score 0.55
• genetic disorder · score 0.49
• autosomal recessive hypohidrotic ectodermal dysplasia · score 0.37
• Microcephaly · score 0.34
• Encephalopathy · score 0.34
• Global brain atrophy · score 0.34
• Aplasia/Hypoplasia of the corpus callosum · score 0.34
• Severe global developmental delay · score 0.34

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Amino-acid sequence (98 residues)

External references