About Platelet-derived growth factor subunit A
Platelet-derived growth factor subunit A (PDGFA) is a protein
from Homo sapiens identified by UniProt accession
P04085, 211 residues long.
MolForge cross-references it against 0 known binders and
365 disease associations.
Target properties
| Protein name | Platelet-derived growth factor subunit A |
|---|
| UniProt accession | P04085 |
|---|
| Gene | PDGFA |
|---|
| Organism | Homo sapiens |
|---|
| Length | 211 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (365)
Diseases linked to this target (Open Targets).
- hair shape measurement · score 0.44
- puberty onset measurement · score 0.42
- cancer · score 0.38
- age at first facial hair · score 0.36
- alopecia · score 0.36
- balding measurement · score 0.32
- low grade glioma · score 0.28
- lung adenocarcinoma · score 0.27
- ulcerative colitis · score 0.26
- endometrial cancer · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P04085-F1 | alphafold | PREDICTED | 78.02 | — |
Amino-acid sequence (211 residues)
MRTLACLLLL GCGYLAHVLA EEAEIPREVI ERLARSQIHS IRDLQRLLEI DSVGSEDSLD TSLRAHGVHA TKHVPEKRPL PIRRKRSIEE AVPAVCKTRT VIYEIPRSQV DPTSANFLIW PPCVEVKRCT GCCNTSSVKC QPSRVHHRSV KVAKVEYVRK KPKLKEVQVR LEEHLECACA TTSLNPDYRE EDTGRPRESG KKRKRKRLKP T
Explore Platelet-derived growth factor subunit A with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets