Prorelaxin H2 (RLN2)

About Prorelaxin H2

Prorelaxin H2 (RLN2) is a protein from Homo sapiens identified by UniProt accession P04090, 185 residues long. MolForge cross-references it against 0 known binders and 148 disease associations.

Target properties

Protein name	Prorelaxin H2
UniProt accession	P04090
Gene	RLN2
Organism	Homo sapiens
Length	185 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (148)

Diseases linked to this target (Open Targets).

glioblastoma multiforme · score 0.25
lung adenocarcinoma · score 0.18
cutaneous melanoma · score 0.18
breast adenocarcinoma · score 0.17
platelet crit · score 0.16
platelet count · score 0.14
squamous cell lung carcinoma · score 0.12
neoplasm · score 0.09
osteosarcoma · score 0.09
metabolite measurement · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P04090-F1	alphafold	PREDICTED	62.52	—

Amino-acid sequence (185 residues)

MPRLFFFHLL GVCLLLNQFS RAVADSWMEE VIKLCGRELV RAQIAICGMS TWSKRSLSQE DAPQTPRPVA EIVPSFINKD TETINMMSEF VANLPQELKL TLSEMQPALP QLQQHVPVLK DSSLLFEEFK KLIRNRQSEA ADSSPSELKY LGLDTHSRKK RQLYSALANK CCHVGCTKRS LARFC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards