About Colipase
Colipase (CLPS) is a protein
from Homo sapiens identified by UniProt accession
P04118, 112 residues long.
MolForge cross-references it against 0 known binders and
84 disease associations.
Target properties
| Protein name | Colipase |
|---|
| UniProt accession | P04118 |
|---|
| Gene | CLPS |
|---|
| Organism | Homo sapiens |
|---|
| Length | 112 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (84)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.38
- lung adenocarcinoma · score 0.23
- cutaneous melanoma · score 0.21
- mean reticulocyte volume · score 0.07
- mean corpuscular volume · score 0.06
- hypertriglyceridemia 2 · score 0.06
- mean corpuscular hemoglobin concentration · score 0.06
- cholesterol-ester transfer protein deficiency · score 0.06
- Immature Reticulocyte Fraction Measurement · score 0.06
- thyroid hormone metabolism, abnormal, 2 · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P04118-F1 | alphafold | PREDICTED | 87.88 | — |
Amino-acid sequence (112 residues)
MEKILILLLV ALSVAYAAPG PRGIIINLEN GELCMNSAQC KSNCCQHSSA LGLARCTSMA SENSECSVKT LYGIYYKCPC ERGLTCEGDK TIVGSITNTN FGICHDAGRS KQ
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