About Proto-oncogene Mas
Proto-oncogene Mas (MAS1) is a protein
from Homo sapiens identified by UniProt accession
P04201, 325 residues long.
MolForge cross-references it against 0 known binders and
387 disease associations.
Target properties
| Protein name | Proto-oncogene Mas |
|---|
| UniProt accession | P04201 |
|---|
| Gene | MAS1 |
|---|
| Organism | Homo sapiens |
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| Length | 325 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (387)
Diseases linked to this target (Open Targets).
- lipoprotein A measurement · score 0.26
- COVID-19 · score 0.11
- cancer · score 0.09
- nephrotic syndrome · score 0.09
- familial idiopathic steroid-resistant nephrotic syndrome · score 0.08
- focal segmental glomerulosclerosis · score 0.08
- subarachnoid hemorrhage · score 0.08
- respiratory failure · score 0.07
- blood protein measurement · score 0.07
- IGF-1 measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P04201-F1 | alphafold | PREDICTED | 83.51 | — |
Amino-acid sequence (325 residues)
MDGSNVTSFV VEEPTNISTG RNASVGNAHR QIPIVHWVIM SISPVGFVEN GILLWFLCFR MRRNPFTVYI THLSIADISL LFCIFILSID YALDYELSSG HYYTIVTLSV TFLFGYNTGL YLLTAISVER CLSVLYPIWY RCHRPKYQSA LVCALLWALS CLVTTMEYVM CIDREEESHS RNDCRAVIIF IAILSFLVFT PLMLVSSTIL VVKIRKNTWA SHSSKLYIVI MVTIIIFLIF AMPMRLLYLL YYEYWSTFGN LHHISLLFST INSSANPFIY FFVGSSKKKR FKESLKVVLT RAFKDEMQPR RQKDNCNTVT VETVV
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