Immunoglobulin lambda variable 7-43 (IGLV7-43)

About Immunoglobulin lambda variable 7-43

Immunoglobulin lambda variable 7-43 (IGLV7-43) is a protein from Homo sapiens identified by UniProt accession P04211, 117 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

Target properties

Protein name	Immunoglobulin lambda variable 7-43
UniProt accession	P04211
Gene	IGLV7-43
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (10)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
Barrett's esophagus · score 0.04
Crohn's disease · score 0.03
periodontitis · score 0.01
ulcerative colitis · score 0.01
colorectal cancer · score 0.00
hepatocellular carcinoma · score 0.00
cutaneous lupus erythematosus · score 0.00
relapsing-remitting multiple sclerosis · score 0.00
idiopathic pulmonary fibrosis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P04211-F1	alphafold	PREDICTED	89.42	—

Amino-acid sequence (117 residues)

MAWTPLFLFL LTCCPGSNSQ TVVTQEPSLT VSPGGTVTLT CASSTGAVTS GYYPNWFQQK PGQAPRALIY STSNKHSWTP ARFSGSLLGG KAALTLSGVQ PEDEAEYYCL LYYGGAQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards