Thy-1 membrane glycoprotein (THY1)

About Thy-1 membrane glycoprotein

Thy-1 membrane glycoprotein (THY1) is a protein from Homo sapiens identified by UniProt accession P04216, 161 residues long. MolForge cross-references it against 0 known binders and 548 disease associations.

Target properties

Protein name	Thy-1 membrane glycoprotein
UniProt accession	P04216
Gene	THY1
Organism	Homo sapiens
Length	161 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (548)

Diseases linked to this target (Open Targets).

glomerular filtration rate · score 0.19
mathematical ability · score 0.16
hepatocellular carcinoma · score 0.12
neoplasm · score 0.12
cancer · score 0.10
gut microbiome measurement · score 0.09
malignant pleural mesothelioma · score 0.08
melanoma · score 0.08
systemic scleroderma · score 0.08
glioblastoma multiforme · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P04216-F1	alphafold	PREDICTED	82.65	—

Amino-acid sequence (161 residues)

MNLAISIALL LTVLQVSRGQ KVTSLTACLV DQSLRLDCRH ENTSSSPIQY EFSLTRETKK HVLFGTVGVP EHTYRSRTNF TSKYNMKVLY LSAFTSKDEG TYTCALHHSG HSPPISSQNV TVLRDKLVKC EGISLLAQNT SWLLLLLLSL SLLQATDFMS L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards