Protein S100-B (S100B)

About Protein S100-B

Protein S100-B (S100B) is a protein from Homo sapiens identified by UniProt accession P04271, 92 residues long. MolForge cross-references it against 0 known binders and 835 disease associations.

Target properties

Protein name	Protein S100-B
UniProt accession	P04271
Gene	S100B
Organism	Homo sapiens
Length	92 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (1)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (835)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.35
head and neck squamous cell carcinoma · score 0.20
lymphocyte count · score 0.17
cutaneous melanoma · score 0.14
melanoma · score 0.11
neoplasm · score 0.11
Delirium · score 0.11
major depressive disorder · score 0.11
t-tau:beta-amyloid 1-42 ratio measurement · score 0.11
schizophrenia · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P04271-F1	alphafold	PREDICTED	91.41	—

Amino-acid sequence (92 residues)

MSELEKAMVA LIDVFHQYSG REGDKHKLKK SELKELINNE LSHFLEEIKE QEVVDKVMET LDNDGDGECD FQEFMAFVAM VTTACHEFFE HE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards