Immunoglobulin kappa variable 1D-39 (IGKV1D-39)

About Immunoglobulin kappa variable 1D-39

Immunoglobulin kappa variable 1D-39 (IGKV1D-39) is a protein from Homo sapiens identified by UniProt accession P04432, 117 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein name	Immunoglobulin kappa variable 1D-39
UniProt accession	P04432
Gene	IGKV1D-39
Organism	Homo sapiens
Length	117 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (15)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
Barrett's esophagus · score 0.04
esophageal adenocarcinoma · score 0.04
ulcerative colitis · score 0.02
Crohn's disease · score 0.02
squamous cell carcinoma · score 0.01
idiopathic pulmonary fibrosis · score 0.01
breast cancer · score 0.01
pancreatic neoplasm · score 0.01
Leishmaniasis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P04432-F1	alphafold	PREDICTED	90.69	—

Amino-acid sequence (117 residues)

MDMRVPAQLL GLLLLWLRGA RCDIQMTQSP SSLSASVGDR VTITCRASQS ISSYLNWYQQ KPGKAPKLLI YAASSLQSGV PSRFSGSGSG TDFTLTISSL QPEDFATYYC QQSYSTP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards