T cell receptor beta variable 7-9 (TRBV7-9)

About T cell receptor beta variable 7-9

T cell receptor beta variable 7-9 (TRBV7-9) is a protein from Homo sapiens identified by UniProt accession P04435, 115 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.

Target properties

Protein name	T cell receptor beta variable 7-9
UniProt accession	P04435
Gene	TRBV7-9
Organism	Homo sapiens
Length	115 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (4)

Diseases linked to this target (Open Targets).

chronic kidney disease · score 0.04
COVID-19 · score 0.02
myelodysplastic syndrome · score 0.00
neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P04435-F1	alphafold	PREDICTED	90.05	—

Amino-acid sequence (115 residues)

MGTSLLCWMA LCLLGADHAD TGVSQNPRHK ITKRGQNVTF RCDPISEHNR LYWYRQTLGQ GPEFLTYFQN EAQLEKSRLL SDRFSAERPK GSFSTLEIQR TEQGDSAMYL CASSL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards