T cell receptor alpha variable 29/delta variable 5…

About T cell receptor alpha variable 29/delta variable 5

T cell receptor alpha variable 29/delta variable 5 (TRAV29DV5) is a protein from Homo sapiens identified by UniProt accession P04437, 119 residues long. MolForge cross-references it against 0 known binders and 152 disease associations.

Target properties

Protein name	T cell receptor alpha variable 29/delta variable 5
UniProt accession	P04437
Gene	TRAV29DV5
Organism	Homo sapiens
Length	119 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (152)

Diseases linked to this target (Open Targets).

neoplasm · score 0.05
inflammatory bowel disease · score 0.04
chronic kidney disease · score 0.04
COVID-19 · score 0.04
infect · score 0.03
infection · score 0.03
graft versus host disease · score 0.03
breast ductal carcinoma in situ · score 0.03
experimental autoimmune encephalomyelitis · score 0.03
cancer · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P04437-F1	alphafold	PREDICTED	86.88	—

Amino-acid sequence (119 residues)

MAMLLGASVL ILWLQPDWVN SQQKNDDQQV KQNSPSLSVQ EGRISILNCD YTNSMFDYFL WYKKYPAEGP TFLISISSIK DKNEDGRFTV FLNKSAKHLS LHIVPSQPGD SAVYFCAAS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

T cell receptor alpha variable 29/delta variable 5 (TRAV29DV5)