Metallothionein-1E (MT1E)

About Metallothionein-1E

Metallothionein-1E (MT1E) is a protein from Homo sapiens identified by UniProt accession P04732, 61 residues long. MolForge cross-references it against 0 known binders and 110 disease associations.

Target properties

Protein name	Metallothionein-1E
UniProt accession	P04732
Gene	MT1E
Organism	Homo sapiens
Length	61 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (110)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.34
hepatocellular carcinoma · score 0.10
adolescent idiopathic scoliosis · score 0.04
schizophrenia · score 0.04
neoplasm · score 0.02
medulloblastoma · score 0.02
Kidney Oncocytoma · score 0.02
breast cancer · score 0.02
malignant glioma · score 0.02
preeclampsia · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P04732-F1	alphafold	PREDICTED	81.11	—

Amino-acid sequence (61 residues)

MDPNCSCATG GSCTCAGSCK CKECKCTSCK KSCCSCCPVG CAKCAQGCVC KGASEKCSCC A

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards