Metallothionein-1F (MT1F)

About Metallothionein-1F

Metallothionein-1F (MT1F) is a protein from Homo sapiens identified by UniProt accession P04733, 61 residues long. MolForge cross-references it against 0 known binders and 92 disease associations.

Target properties

Protein name	Metallothionein-1F
UniProt accession	P04733
Gene	MT1F
Organism	Homo sapiens
Length	61 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (92)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.50
hepatocellular carcinoma · score 0.10
neoplasm · score 0.04
gonorrhea · score 0.03
ulcerative colitis · score 0.03
clear cell renal carcinoma · score 0.03
Kidney Oncocytoma · score 0.02
colorectal cancer · score 0.02
gastric cardia carcinoma · score 0.02
acute myeloid leukemia · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P04733-F1	alphafold	PREDICTED	79.55	—

Amino-acid sequence (61 residues)

MDPNCSCAAG VSCTCAGSCK CKECKCTSCK KSCCSCCPVG CSKCAQGCVC KGASEKCSCC D

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards