About Prorelaxin H1
Prorelaxin H1 (RLN1) is a protein
from Homo sapiens identified by UniProt accession
P04808, 185 residues long.
MolForge cross-references it against 0 known binders and
86 disease associations.
Target properties
| Protein name | Prorelaxin H1 |
|---|
| UniProt accession | P04808 |
|---|
| Gene | RLN1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 185 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (86)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.19
- breast adenocarcinoma · score 0.18
- low grade glioma · score 0.17
- body fat percentage · score 0.09
- metabolite measurement · score 0.06
- platelet crit · score 0.06
- Isolated follicle stimulating hormone deficiency · score 0.05
- azoospermia · score 0.05
- Kallmann syndrome · score 0.05
- partial androgen insensitivity syndrome · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P04808-F1 | alphafold | PREDICTED | 61.39 | — |
Amino-acid sequence (185 residues)
MPRLFLFHLL EFCLLLNQFS RAVAAKWKDD VIKLCGRELV RAQIAICGMS TWSKRSLSQE DAPQTPRPVA EIVPSFINKD TETIIIMLEF IANLPPELKA ALSERQPSLP ELQQYVPALK DSNLSFEEFK KLIRNRQSEA ADSNPSELKY LGLDTHSQKK RRPYVALFEK CCLIGCTKRS LAKYC
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