Interferon alpha-4 (IFNA4)

About Interferon alpha-4

Interferon alpha-4 (IFNA4) is a protein from Homo sapiens identified by UniProt accession P05014, 189 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.

Target properties

Protein name	Interferon alpha-4
UniProt accession	P05014
Gene	IFNA4
Organism	Homo sapiens
Length	189 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (58)

Diseases linked to this target (Open Targets).

lung adenocarcinoma · score 0.18
CINCA syndrome · score 0.18
thyroid gland adenocarcinoma · score 0.18
breast adenocarcinoma · score 0.18
esophageal cancer · score 0.15
systemic lupus erythematosus · score 0.11
dermatomyositis · score 0.04
drug use measurement · score 0.04
psoriasis · score 0.04
body height · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P05014-F1	alphafold	PREDICTED	85.06	—

Amino-acid sequence (189 residues)

MALSFSLLMA VLVLSYKSIC SLGCDLPQTH SLGNRRALIL LAQMGRISHF SCLKDRHDFG FPEEEFDGHQ FQKAQAISVL HEMIQQTFNL FSTEDSSAAW EQSLLEKFST ELYQQLNDLE ACVIQEVGVE ETPLMNEDSI LAVRKYFQRI TLYLTEKKYS PCAWEVVRAE IMRSLSFSTN LQKRLRRKD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards