Interferon alpha-16 (IFNA16)

About Interferon alpha-16

Interferon alpha-16 (IFNA16) is a protein from Homo sapiens identified by UniProt accession P05015, 189 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.

Target properties

Protein name	Interferon alpha-16
UniProt accession	P05015
Gene	IFNA16
Organism	Homo sapiens
Length	189 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (19)

Diseases linked to this target (Open Targets).

lung adenocarcinoma · score 0.18
systemic lupus erythematosus · score 0.11
drug use measurement · score 0.04
essential thrombocythemia · score 0.04
dermatomyositis · score 0.04
psoriasis · score 0.04
body height · score 0.03
lupus nephritis · score 0.01
Thrombocytosis · score 0.01
type 2 diabetes mellitus · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P05015-F1	alphafold	PREDICTED	83.83	—

Amino-acid sequence (189 residues)

MALSFSLLMA VLVLSYKSIC SLGCDLPQTH SLGNRRALIL LAQMGRISHF SCLKDRYDFG FPQEVFDGNQ FQKAQAISAF HEMIQQTFNL FSTKDSSAAW DETLLDKFYI ELFQQLNDLE ACVTQEVGVE EIALMNEDSI LAVRKYFQRI TLYLMGKKYS PCAWEVVRAE IMRSFSFSTN LQKGLRRKD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards