Apolipoprotein D (APOD)

About Apolipoprotein D

Apolipoprotein D (APOD) is a protein from Homo sapiens identified by UniProt accession P05090, 189 residues long. MolForge cross-references it against 0 known binders and 258 disease associations.

Target properties

Protein name	Apolipoprotein D
UniProt accession	P05090
Gene	APOD
Organism	Homo sapiens
Length	189 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (258)

Diseases linked to this target (Open Targets).

cutaneous melanoma · score 0.15
cancer · score 0.08
gonorrhea · score 0.08
Pick disease · score 0.06
body height · score 0.06
gestational diabetes · score 0.05
irritable bowel syndrome · score 0.05
myeloid sarcoma · score 0.05
cerebral amyloid angiopathy · score 0.04
neoplasm · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P05090-F1	alphafold	PREDICTED	89.93	—

Amino-acid sequence (189 residues)

MVMLLLLLSA LAGLFGAAEG QAFHLGKCPN PPVQENFDVN KYLGRWYEIE KIPTTFENGR CIQANYSLME NGKIKVLNQE LRADGTVNQI EGEATPVNLT EPAKLEVKFS WFMPSAPYWI LATDYENYAL VYSCTCIIQL FHVDFAWILA RNPNLPPETV DSLKNILTSN NIDVKKMTVT DQVNCPKLS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards