About Inhibin alpha chain
Inhibin alpha chain (INHA) is a protein
from Homo sapiens identified by UniProt accession
P05111, 366 residues long.
MolForge cross-references it against 0 known binders and
280 disease associations.
Target properties
| Protein name | Inhibin alpha chain |
|---|
| UniProt accession | P05111 |
|---|
| Gene | INHA |
|---|
| Organism | Homo sapiens |
|---|
| Length | 366 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (280)
Diseases linked to this target (Open Targets).
- cutaneous melanoma · score 0.18
- cortical thickness · score 0.14
- body height · score 0.14
- neoplasm · score 0.11
- lung adenocarcinoma · score 0.08
- adrenal cortex carcinoma · score 0.08
- appendicular lean mass · score 0.08
- primary ovarian insufficiency · score 0.07
- 46,XX gonadal dysgenesis · score 0.07
- cancer · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P05111-F1 | alphafold | PREDICTED | 70.17 | — |
Amino-acid sequence (366 residues)
MVLHLLLFLL LTPQGGHSCQ GLELARELVL AKVRALFLDA LGPPAVTREG GDPGVRRLPR RHALGGFTHR GSEPEEEEDV SQAILFPATD ASCEDKSAAR GLAQEAEEGL FRYMFRPSQH TRSRQVTSAQ LWFHTGLDRQ GTAASNSSEP LLGLLALSPG GPVAVPMSLG HAPPHWAVLH LATSALSLLT HPVLVLLLRC PLCTCSARPE ATPFLVAHTR TRPPSGGERA RRSTPLMSWP WSPSALRLLQ RPPEEPAAHA NCHRVALNIS FQELGWERWI VYPPSFIFHY CHGGCGLHIP PNLSLPVPGA PPTPAQPYSL LPGAQPCCAA LPGTMRPLHV RTTSDGGYSF KYETVPNLLT QHCACI
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