Interleukin-5 (IL5)

About Interleukin-5

Interleukin-5 (IL5) is a protein from Homo sapiens identified by UniProt accession P05113, 134 residues long. MolForge cross-references it against 0 known binders and 1,034 disease associations.

Target properties

Protein name	Interleukin-5
UniProt accession	P05113
Gene	IL5
Organism	Homo sapiens
Length	134 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Approved drugs hitting this target (8)

DrugCentral-linked approved drugs that act on this protein.

Disease associations (1034)

Diseases linked to this target (Open Targets).

asthma · score 0.62
Hypereosinophilic syndrome · score 0.51
chronic rhinosinusitis with nasal polyps · score 0.49
Airway obstruction · score 0.46
chronic obstructive pulmonary disease · score 0.39
Nasal Cavity Polyp · score 0.39
eosinophil percentage of leukocytes · score 0.38
eosinophil count · score 0.38
chronic rhinosinusitis · score 0.37
vasculitis · score 0.37

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P05113-F1	alphafold	PREDICTED	86.68	—

Amino-acid sequence (134 residues)

MRMLLHLSLL ALGAAYVYAI PTEIPTSALV KETLALLSTH RTLLIANETL RIPVPVHKNH QLCTEEIFQG IGTLESQTVQ GGTVERLFKN LSLIKKYIDG QKKKCGEERR RVNQFLDYLQ EFLGVMNTEW IIES

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards