Galectin-2 (LGALS2)

About Galectin-2

Galectin-2 (LGALS2) is a protein from Homo sapiens identified by UniProt accession P05162, 132 residues long. MolForge cross-references it against 0 known binders and 219 disease associations.

Target properties

Protein name	Galectin-2
UniProt accession	P05162
Gene	LGALS2
Organism	Homo sapiens
Length	132 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (219)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.29
neurodegenerative disease · score 0.21
myocardial infarction · score 0.19
neoplasm · score 0.09
triple-negative breast cancer · score 0.08
papillary thyroid carcinoma · score 0.07
gestational diabetes · score 0.07
fetal growth restriction · score 0.07
isolated agammaglobulinemia · score 0.06
common variable immunodeficiency · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P05162-F1	alphafold	PREDICTED	96.57	—

Amino-acid sequence (132 residues)

MTGELEVKNM DMKPGSTLKI TGSIADGTDG FVINLGQGTD KLNLHFNPRF SESTIVCNSL DGSNWGQEQR EDHLCFSPGS EVKFTVTFES DKFKVKLPDG HELTFPNRLG HSHLSYLSVR GGFNMSSFKL KE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards