Large ribosomal subunit protein P2 (RPLP2)

About Large ribosomal subunit protein P2

Large ribosomal subunit protein P2 (RPLP2) is a protein from Homo sapiens identified by UniProt accession P05387, 115 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.

Target properties

Protein name	Large ribosomal subunit protein P2
UniProt accession	P05387
Gene	RPLP2
Organism	Homo sapiens
Length	115 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (50)

Diseases linked to this target (Open Targets).

influenza · score 0.46
neurodegenerative disease · score 0.18
hepatocellular carcinoma · score 0.10
breast carcinoma · score 0.07
BMI-adjusted waist-hip ratio · score 0.06
BMI-adjusted waist circumference · score 0.05
neoplasm · score 0.05
cancer · score 0.05
HbA1c measurement · score 0.03
body fat distribution · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P05387-F1	alphafold	PREDICTED	67.83	—

Amino-acid sequence (115 residues)

MRYVASYLLA ALGGNSSPSA KDIKKILDSV GIEADDDRLN KVISELNGKN IEDVIAQGIG KLASVPAGGA VAVSAAPGSA APAAGSAPAA AEEKKDEKKE ESEESDDDMG FGLFD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards