About Neuroendocrine protein 7B2
Neuroendocrine protein 7B2 (SCG5) is a protein
from Homo sapiens identified by UniProt accession
P05408, 212 residues long.
MolForge cross-references it against 0 known binders and
141 disease associations.
Target properties
| Protein name | Neuroendocrine protein 7B2 |
|---|
| UniProt accession | P05408 |
|---|
| Gene | SCG5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 212 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (141)
Diseases linked to this target (Open Targets).
- hereditary mixed polyposis syndrome · score 0.36
- BMI-adjusted waist circumference · score 0.35
- colorectal cancer · score 0.14
- chin morphology measurement · score 0.12
- colorectal adenoma · score 0.10
- mean corpuscular volume · score 0.08
- mean corpuscular hemoglobin · score 0.08
- sleep measurement · score 0.07
- Red cell distribution width · score 0.07
- mean corpuscular hemoglobin concentration · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P05408-F1 | alphafold | PREDICTED | 62.47 | — |
Amino-acid sequence (212 residues)
MVSRMVSTML SGLLFWLASG WTPAFAYSPR TPDRVSEADI QRLLHGVMEQ LGIARPRVEY PAHQAMNLVG PQSIEGGAHE GLQHLGPFGN IPNIVAELTG DNIPKDFSED QGYPDPPNPC PVGKTADDGC LENTPDTAEF SREFQLHQHL FDPEHDYPGL GKWNKKLLYE KMKGGERRKR RSVNPYLQGQ RLDNVVAKKS VPHFSDEDKD PE
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