About Tetranectin
Tetranectin (CLEC3B) is a protein
from Homo sapiens identified by UniProt accession
P05452, 202 residues long.
MolForge cross-references it against 0 known binders and
169 disease associations.
Target properties
| Protein name | Tetranectin |
|---|
| UniProt accession | P05452 |
|---|
| Gene | CLEC3B |
|---|
| Organism | Homo sapiens |
|---|
| Length | 202 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (169)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.31
- blood protein measurement · score 0.23
- Parkinson disease · score 0.22
- Alzheimer disease · score 0.22
- lysosomal storage disease · score 0.22
- multiple sclerosis · score 0.22
- neuroinflammatory disorder · score 0.16
- hepatocellular carcinoma · score 0.11
- neoplasm · score 0.10
- nonpapillary renal cell carcinoma · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P05452-F1 | alphafold | PREDICTED | 87.95 | — |
Amino-acid sequence (202 residues)
MELWGAYLLL CLFSLLTQVT TEPPTQKPKK IVNAKKDVVN TKMFEELKSR LDTLAQEVAL LKEQQALQTV CLKGTKVHMK CFLAFTQTKT FHEASEDCIS RGGTLGTPQT GSENDALYEY LRQSVGNEAE IWLGLNDMAA EGTWVDMTGA RIAYKNWETE ITAQPDGGKT ENCAVLSGAA NGKWFDKRCR DQLPYICQFG IV
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