ATP synthase F(0) complex subunit C1, mitochondrial…

About ATP synthase F(0) complex subunit C1, mitochondrial

ATP synthase F(0) complex subunit C1, mitochondrial (ATP5MC1) is a protein from Homo sapiens identified by UniProt accession P05496, 136 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.

Target properties

Protein name	ATP synthase F(0) complex subunit C1, mitochondrial
UniProt accession	P05496
Gene	ATP5MC1
Organism	Homo sapiens
Length	136 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (74)

Diseases linked to this target (Open Targets).

body height · score 0.23
forced expiratory volume · score 0.17
refractive error measurement · score 0.17
coronary artery disease · score 0.16
type 2 diabetes mellitus · score 0.15
platelet count · score 0.15
high density lipoprotein cholesterol measurement · score 0.14
self reported educational attainment · score 0.13
bilirubin measurement · score 0.11
triglyceride measurement · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P05496-F1	alphafold	PREDICTED	74.01	—

Amino-acid sequence (136 residues)

MQTAGALFIS PALIRCCTRG LIRPVSASFL NSPVNSSKQP SYSNFPLQVA RREFQTSVVS RDIDTAAKFI GAGAATVGVA GSGAGIGTVF GSLIIGYARN PSLKQQLFSY AILGFALSEA MGLFCLMVAF LILFAM

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

ATP synthase F(0) complex subunit C1, mitochondrial (ATP5MC1)