About Beta-casein
Beta-casein (CSN2) is a protein
from Homo sapiens identified by UniProt accession
P05814, 226 residues long.
MolForge cross-references it against 0 known binders and
53 disease associations.
Target properties
| Protein name | Beta-casein |
|---|
| UniProt accession | P05814 |
|---|
| Gene | CSN2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 226 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (53)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- lung adenocarcinoma · score 0.18
- glioblastoma multiforme · score 0.18
- head and neck squamous cell carcinoma · score 0.18
- cutaneous melanoma · score 0.13
- breast carcinoma · score 0.08
- type 1 diabetes mellitus · score 0.03
- diabetes mellitus · score 0.02
- pulse pressure measurement · score 0.02
- Myocardial Ischemia · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P05814-F1 | alphafold | PREDICTED | 60.39 | — |
Amino-acid sequence (226 residues)
MKVLILACLV ALALARETIE SLSSSEESIT EYKQKVEKVK HEDQQQGEDE HQDKIYPSFQ PQPLIYPFVE PIPYGFLPQN ILPLAQPAVV LPVPQPEIME VPKAKDTVYT KGRVMPVLKS PTIPFFDPQI PKLTDLENLH LPLPLLQPLM QQVPQPIPQT LALPPQPLWS VPQPKVLPIP QQVVPYPQRA VPVQALLLNQ ELLLNPTHQI YPVTQPLAPV HNPISV
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