About Calbindin
Calbindin (CALB1) is a protein
from Homo sapiens identified by UniProt accession
P05937, 261 residues long.
MolForge cross-references it against 0 known binders and
315 disease associations.
Target properties
| Protein name | Calbindin |
|---|
| UniProt accession | P05937 |
|---|
| Gene | CALB1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 261 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (315)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- protein measurement · score 0.42
- smoking status measurement · score 0.33
- attention deficit hyperactivity disorder · score 0.26
- substance abuse · score 0.25
- antisocial behaviour measurement · score 0.25
- clear cell renal carcinoma · score 0.09
- cancer · score 0.08
- Parkinson disease · score 0.08
- neoplasm · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P05937-F1 | alphafold | PREDICTED | 82.63 | — |
Amino-acid sequence (261 residues)
MAESHLQSSL ITASQFFEIW LHFDADGSGY LEGKELQNLI QELQQARKKA GLELSPEMKT FVDQYGQRDD GKIGIVELAH VLPTEENFLL LFRCQQLKSC EEFMKTWRKY DTDHSGFIET EELKNFLKDL LEKANKTVDD TKLAEYTDLM LKLFDSNNDG KLELTEMARL LPVQENFLLK FQGIKMCGKE FNKAFELYDQ DGNGYIDENE LDALLKDLCE KNKQDLDINN ITTYKKNIMA LSDGGKLYRT DLALILCAGD N
Explore Calbindin with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets