Glycophorin-B (GYPB)

About Glycophorin-B

Glycophorin-B (GYPB) is a protein from Homo sapiens identified by UniProt accession P06028, 91 residues long. MolForge cross-references it against 0 known binders and 191 disease associations.

Target properties

Protein name	Glycophorin-B
UniProt accession	P06028
Gene	GYPB
Organism	Homo sapiens
Length	91 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (191)

Diseases linked to this target (Open Targets).

reticulocyte count · score 0.52
reticulocyte measurement · score 0.43
Red cell distribution width · score 0.43
platelet count · score 0.42
Immature Reticulocyte Fraction Measurement · score 0.41
mean corpuscular volume · score 0.40
malaria · score 0.38
mean reticulocyte volume · score 0.36
HbA1c measurement · score 0.36
platelet crit · score 0.31

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P06028-F1	alphafold	PREDICTED	66.13	—

Amino-acid sequence (91 residues)

MYGKIIFVLL LSEIVSISAL STTEVAMHTS TSSSVTKSYI SSQTNGETGQ LVHRFTVPAP VVIILIILCV MAGIIGTILL ISYSIRRLIK A

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards