T-cell surface glycoprotein CD1a (CD1A)

About T-cell surface glycoprotein CD1a

T-cell surface glycoprotein CD1a (CD1A) is a protein from Homo sapiens identified by UniProt accession P06126, 327 residues long. MolForge cross-references it against 0 known binders and 61 disease associations.

Target properties

Protein name	T-cell surface glycoprotein CD1a
UniProt accession	P06126
Gene	CD1A
Organism	Homo sapiens
Length	327 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (61)

Diseases linked to this target (Open Targets).

neurofilament light chain measurement · score 0.26
leukocyte count · score 0.19
neutrophil count · score 0.19
pancreatic adenocarcinoma · score 0.18
sphingomyelin measurement · score 0.05
Barrett's esophagus · score 0.04
papillary thyroid carcinoma · score 0.03
oral lichen planus · score 0.03
neoplasm · score 0.02
reticulocyte measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P06126-F1	alphafold	PREDICTED	88.61	—

Amino-acid sequence (327 residues)

MLFLLLPLLA VLPGDGNADG LKEPLSFHVT WIASFYNHSW KQNLVSGWLS DLQTHTWDSN SSTIVFLCPW SRGNFSNEEW KELETLFRIR TIRSFEGIRR YAHELQFEYP FEIQVTGGCE LHSGKVSGSF LQLAYQGSDF VSFQNNSWLP YPVAGNMAKH FCKVLNQNQH ENDITHNLLS DTCPRFILGL LDAGKAHLQR QVKPEAWLSH GPSPGPGHLQ LVCHVSGFYP KPVWVMWMRG EQEQQGTQRG DILPSADGTW YLRATLEVAA GEAADLSCRV KHSSLEGQDI VLYWEHHSSV GFIILAVIVP LLLLIGLALW FRKRCFC

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards