Immunoglobulin kappa variable 2-30 (IGKV2-30)

About Immunoglobulin kappa variable 2-30

Immunoglobulin kappa variable 2-30 (IGKV2-30) is a protein from Homo sapiens identified by UniProt accession P06310, 120 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Immunoglobulin kappa variable 2-30
UniProt accession	P06310
Gene	IGKV2-30
Organism	Homo sapiens
Length	120 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	LOW
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

cutaneous Leishmaniasis · score 0.59
Barrett's esophagus · score 0.05
squamous cell carcinoma · score 0.04
esophageal adenocarcinoma · score 0.04
idiopathic pulmonary fibrosis · score 0.01
adenomatous colon polyp · score 0.00
Crohn's disease · score 0.00
Lyme disease · score 0.00
relapsing-remitting multiple sclerosis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P06310-F1	alphafold	PREDICTED	90.48	—

Amino-acid sequence (120 residues)

MRLPAQLLGL LMLWVPGSSG DVVMTQSPLS LPVTLGQPAS ISCRSSQSLV YSDGNTYLNW FQQRPGQSPR RLIYKVSNRD SGVPDRFSGS GSGTDFTLKI SRVEAEDVGV YYCMQGTHWP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards