About Corticoliberin
Corticoliberin (CRH) is a protein
from Homo sapiens identified by UniProt accession
P06850, 196 residues long.
MolForge cross-references it against 0 known binders and
725 disease associations.
Target properties
| Protein name | Corticoliberin |
|---|
| UniProt accession | P06850 |
|---|
| Gene | CRH |
|---|
| Organism | Homo sapiens |
|---|
| Length | 196 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (725)
Diseases linked to this target (Open Targets).
- body mass index · score 0.39
- autosomal dominant nocturnal frontal lobe epilepsy · score 0.37
- body weight · score 0.27
- body height · score 0.25
- PHF-tau measurement · score 0.25
- waist circumference · score 0.25
- anxiety · score 0.11
- lean body mass · score 0.10
- irritable bowel syndrome · score 0.10
- inflammatory bowel disease · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P06850-F1 | alphafold | PREDICTED | 61.96 | — |
Amino-acid sequence (196 residues)
MRLPLLVSAG VLLVALLPCP PCRALLSRGP VPGARQAPQH PQPLDFFQPP PQSEQPQQPQ ARPVLLRMGE EYFLRLGNLN KSPAAPLSPA SSLLAGGSGS RPSPEQATAN FFRVLLQQLL LPRRSLDSPA ALAERGARNA LGGHQEAPER ERRSEEPPIS LDLTFHLLRE VLEMARAEQL AQQAHSNRKL MEIIGK
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