Acyl-CoA-binding protein (DBI)

About Acyl-CoA-binding protein

Acyl-CoA-binding protein (DBI) is a protein from Homo sapiens identified by UniProt accession P07108, 87 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.

Target properties

Protein name	Acyl-CoA-binding protein
UniProt accession	P07108
Gene	DBI
Organism	Homo sapiens
Length	87 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (79)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.42
protein measurement · score 0.25
neuroinflammatory disorder · score 0.19
metabolite measurement · score 0.11
glioblastoma multiforme · score 0.08
glycogen storage disease VI · score 0.05
progressive familial intrahepatic cholestasis · score 0.04
Congenital bile acid synthesis defect type 3 · score 0.04
Crigler-Najjar syndrome type 2 · score 0.04
glycine N-methyltransferase deficiency · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P07108-F1	alphafold	PREDICTED	97.21	—

Amino-acid sequence (87 residues)

MSQAEFEKAA EEVRHLKTKP SDEEMLFIYG HYKQATVGDI NTERPGMLDF TGKAKWDAWN ELKGTSKEDA MKAYINKVEE LKKKYGI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards