About Glutathione peroxidase 1
Glutathione peroxidase 1 (GPX1) is a protein
from Homo sapiens identified by UniProt accession
P07203, 203 residues long.
MolForge cross-references it against 0 known binders and
489 disease associations.
Target properties
| Protein name | Glutathione peroxidase 1 |
|---|
| UniProt accession | P07203 |
|---|
| Gene | GPX1 |
|---|
| Organism | Homo sapiens |
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| Length | 203 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (489)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- Parkinson disease · score 0.30
- multiple sclerosis · score 0.30
- Alzheimer disease · score 0.30
- lysosomal storage disease · score 0.30
- cutaneous melanoma · score 0.23
- gluthathione peroxidase deficiency · score 0.19
- self reported educational attainment · score 0.16
- creatinine measurement · score 0.14
- inflammatory bowel disease · score 0.14
Amino-acid sequence (203 residues)
MCAARLAAAA AAAQSVYAFS ARPLAGGEPV SLGSLRGKVL LIENVASLUG TTVRDYTQMN ELQRRLGPRG LVVLGFPCNQ FGHQENAKNE EILNSLKYVR PGGGFEPNFM LFEKCEVNGA GAHPLFAFLR EALPAPSDDA TALMTDPKLI TWSPVCRNDV AWNFEKFLVG PDGVPLRRYS RRFQTIDIEP DIEALLSQGP SCA
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