Acylphosphatase-1 (ACYP1)

Homo sapiens — UniProt P07311

Gene: ACYP1Homo sapiensSwissProt reviewed

About Acylphosphatase-1

Acylphosphatase-1 (ACYP1) is a protein from Homo sapiens identified by UniProt accession P07311, 99 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.

Target properties

Protein nameAcylphosphatase-1
UniProt accessionP07311
GeneACYP1
OrganismHomo sapiens
Length99 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (51)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.37
  • heel bone mineral density · score 0.20
  • coronary artery disease · score 0.19
  • insulin like growth factor measurement · score 0.18
  • alkaline phosphatase measurement · score 0.17
  • IGF-1 measurement · score 0.16
  • bone density · score 0.15
  • skin aging measurement · score 0.15
  • mean corpuscular hemoglobin · score 0.15
  • skin aging · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P07311-F1alphafoldPREDICTED96.29—

Amino-acid sequence (99 residues)

MAEGNTLISV DYEIFGKVQG VFFRKHTQAE GKKLGLVGWV QNTDRGTVQG QLQGPISKVR HMQEWLETRG SPKSHIDKAN FNNEKVILKL DYSDFQIVK

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Quick facts

UniProtP07311
GeneACYP1
OrganismHomo sapiens
Length99
Binders0
Diseases51
View on UniProt