Metallothionein-1B (MT1B)

About Metallothionein-1B

Metallothionein-1B (MT1B) is a protein from Homo sapiens identified by UniProt accession P07438, 61 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.

Target properties

Protein name	Metallothionein-1B
UniProt accession	P07438
Gene	MT1B
Organism	Homo sapiens
Length	61 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (37)

Diseases linked to this target (Open Targets).

hepatocellular carcinoma · score 0.03
non-alcoholic steatohepatitis · score 0.03
neoplasm · score 0.02
metabolite measurement · score 0.02
non-alcoholic fatty liver disease · score 0.02
non-alcoholic fatty liver · score 0.01
urinary bladder carcinoma · score 0.01
periodontal disorder · score 0.01
Down syndrome · score 0.01
alkaline phosphatase measurement · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P07438-F1	alphafold	PREDICTED	77.60	—

Amino-acid sequence (61 residues)

MDPNCSCTTG GSCACAGSCK CKECKCTSCK KCCCSCCPVG CAKCAQGCVC KGSSEKCRCC A

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards