Kappa-casein (CSN3)

About Kappa-casein

Kappa-casein (CSN3) is a protein from Homo sapiens identified by UniProt accession P07498, 182 residues long. MolForge cross-references it against 0 known binders and 71 disease associations.

Target properties

Protein name	Kappa-casein
UniProt accession	P07498
Gene	CSN3
Organism	Homo sapiens
Length	182 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (71)

Diseases linked to this target (Open Targets).

neoplasm · score 0.07
nervous system disease · score 0.02
type 2 diabetes mellitus · score 0.01
COVID-19 · score 0.01
cancer · score 0.01
atherosclerosis · score 0.01
diabetes mellitus · score 0.01
pulmonary hypertension · score 0.01
breast carcinoma · score 0.01
irritable bowel syndrome · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P07498-F1	alphafold	PREDICTED	58.17	—

Amino-acid sequence (182 residues)

MKSFLLVVNA LALTLPFLAV EVQNQKQPAC HENDERPFYQ KTAPYVPMYY VPNSYPYYGT NLYQRRPAIA INNPYVPRTY YANPAVVRPH AQIPQRQYLP NSHPPTVVRR PNLHPSFIAI PPKKIQDKII IPTINTIATV EPTPAPATEP TVDSVVTPEA FSESIITSTP ETTTVAVTPP TA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards