Cytochrome b-c1 complex subunit 6, mitochondrial…

About Cytochrome b-c1 complex subunit 6, mitochondrial

Cytochrome b-c1 complex subunit 6, mitochondrial (UQCRH) is a protein from Homo sapiens identified by UniProt accession P07919, 91 residues long. MolForge cross-references it against 0 known binders and 34 disease associations.

Target properties

Protein name	Cytochrome b-c1 complex subunit 6, mitochondrial
UniProt accession	P07919
Gene	UQCRH
Organism	Homo sapiens
Length	91 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (34)

Diseases linked to this target (Open Targets).

age at menopause · score 0.10
nonpapillary renal cell carcinoma · score 0.04
venous thromboembolism · score 0.04
neoplasm · score 0.03
hepatocellular carcinoma · score 0.02
cancer · score 0.01
Failure to thrive · score 0.01
renal cell carcinoma · score 0.01
soft tissue sarcoma · score 0.01
Obesity · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P07919-F1	alphafold	PREDICTED	87.64	—

Amino-acid sequence (91 residues)

MGLEDEQKML TESGDPEEEE EEEEELVDPL TTVREQCEQL EKCVKARERL ELCDERVSSR SHTEEDCTEE LFDFLHARDH CVAHKLFNNL K

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Cytochrome b-c1 complex subunit 6, mitochondrial (UQCRH)