Rhodopsin (RHO)

Homo sapiens — UniProt P08100

Gene: RHOHomo sapiensSwissProt reviewed

About Rhodopsin

Rhodopsin (RHO) is a protein from Homo sapiens identified by UniProt accession P08100, 348 residues long. MolForge cross-references it against 0 known binders and 317 disease associations.

Target properties

Protein nameRhodopsin
UniProt accessionP08100
GeneRHO
OrganismHomo sapiens
Length348 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-P08100-F1alphafoldPREDICTED88.74—

Amino-acid sequence (348 residues)

MNGTEGPNFY VPFSNATGVV RSPFEYPQYY LAEPWQFSML AAYMFLLIVL GFPINFLTLY VTVQHKKLRT PLNYILLNLA VADLFMVLGG FTSTLYTSLH GYFVFGPTGC NLEGFFATLG GEIALWSLVV LAIERYVVVC KPMSNFRFGE NHAIMGVAFT WVMALACAAP PLAGWSRYIP EGLQCSCGID YYTLKPEVNN ESFVIYMFVV HFTIPMIIIF FCYGQLVFTV KEAAAQQQES ATTQKAEKEV TRMVIIMVIA FLICWVPYAS VAFYIFTHQG SNFGPIFMTI PAFFAKSAAI YNPVIYIMMN KQFRNCMLTT ICCGKNPLGD DEASATVSKT ETSQVAPA

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Quick facts

UniProtP08100
GeneRHO
OrganismHomo sapiens
Length348
Binders0
Diseases317
View on UniProt