Rho-related GTP-binding protein RhoC (RHOC)

About Rho-related GTP-binding protein RhoC

Rho-related GTP-binding protein RhoC (RHOC) is a protein from Homo sapiens identified by UniProt accession P08134, 193 residues long. MolForge cross-references it against 0 known binders and 176 disease associations.

Target properties

Protein name	Rho-related GTP-binding protein RhoC
UniProt accession	P08134
Gene	RHOC
Organism	Homo sapiens
Length	193 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P08134-F1	alphafold	PREDICTED	93.51	—

Amino-acid sequence (193 residues)

MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYIADIEVDG KQVELALWDT AGQEDYDRLR PLSYPDTDVI LMCFSIDSPD SLENIPEKWT PEVKHFCPNV PIILVGNKKD LRQDEHTRRE LAKMKQEPVR SEEGRDMANR ISAFGYLECS AKTKEGVREV FEMATRAGLQ VRKNKRRRGC PIL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards