About Fibroblast growth factor 4
Fibroblast growth factor 4 (FGF4) is a protein
from Homo sapiens identified by UniProt accession
P08620, 206 residues long.
MolForge cross-references it against 0 known binders and
187 disease associations.
Target properties
| Protein name | Fibroblast growth factor 4 |
|---|
| UniProt accession | P08620 |
|---|
| Gene | FGF4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 206 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (187)
Diseases linked to this target (Open Targets).
- cancer · score 0.60
- bone development disease · score 0.60
- neurodegenerative disease · score 0.53
- craniosynostosis · score 0.37
- ovarian carcinoma · score 0.37
- acrocephalosyndactyly · score 0.37
- female reproductive endometrioid cancer · score 0.37
- cutaneous melanoma · score 0.30
- lung adenocarcinoma · score 0.30
- breast adenocarcinoma · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P08620-F1 | alphafold | PREDICTED | 81.49 | — |
Amino-acid sequence (206 residues)
MSGPGTAAVA LLPAVLLALL APWAGRGGAA APTAPNGTLE AELERRWESL VALSLARLPV AAQPKEAAVQ SGAGDYLLGI KRLRRLYCNV GIGFHLQALP DGRIGGAHAD TRDSLLELSP VERGVVSIFG VASRFFVAMS SKGKLYGSPF FTDECTFKEI LLPNNYNAYE SYKYPGMFIA LSKNGKTKKG NRVSPTMKVT HFLPRL
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