Interleukin-3 (IL3)

About Interleukin-3

Interleukin-3 (IL3) is a protein from Homo sapiens identified by UniProt accession P08700, 152 residues long. MolForge cross-references it against 0 known binders and 617 disease associations.

Target properties

Protein name	Interleukin-3
UniProt accession	P08700
Gene	IL3
Organism	Homo sapiens
Length	152 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (617)

Diseases linked to this target (Open Targets).

glioblastoma multiforme · score 0.30
head and neck squamous cell carcinoma · score 0.23
sum of eosinophil and basophil counts · score 0.21
eosinophil percentage of leukocytes · score 0.15
gastric adenocarcinoma · score 0.12
neoplasm · score 0.09
Sepsis · score 0.09
Systemic lupus erythematosus · score 0.08
platelet count · score 0.08
eosinophil count · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P08700-F1	alphafold	PREDICTED	83.33	—

Amino-acid sequence (152 residues)

MSRLPVLLLL QLLVRPGLQA PMTQTTPLKT SWVNCSNMID EIITHLKQPP LPLLDFNNLN GEDQDILMEN NLRRPNLEAF NRAVKSLQNA SAIESILKNL LPCLPLATAA PTRHPIHIKD GDWNEFRRKL TFYLKTLENA QAQQTTLSLA IF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards