Small ribosomal subunit protein eS17 (RPS17)

About Small ribosomal subunit protein eS17

Small ribosomal subunit protein eS17 (RPS17) is a protein from Homo sapiens identified by UniProt accession P08708, 135 residues long. MolForge cross-references it against 0 known binders and 60 disease associations.

Target properties

Protein name	Small ribosomal subunit protein eS17
UniProt accession	P08708
Gene	RPS17
Organism	Homo sapiens
Length	135 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (60)

Diseases linked to this target (Open Targets).

Blackfan-Diamond anemia · score 0.73
Diamond-Blackfan anemia · score 0.62
Duchenne muscular dystrophy · score 0.50
cystic fibrosis · score 0.50
influenza · score 0.46
COVID-19 · score 0.37
severe acute respiratory syndrome · score 0.37
Abnormal radial ray morphology · score 0.37
Becker muscular dystrophy · score 0.29
qualitative or quantitative defects of dystrophin · score 0.26

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P08708-F1	alphafold	PREDICTED	86.28	—

Amino-acid sequence (135 residues)

MGRVRTKTVK KAARVIIEKY YTRLGNDFHT NKRVCEEIAI IPSKKLRNKI AGYVTHLMKR IQRGPVRGIS IKLQEEERER RDNYVPEVSA LDQEIIEVDP DTKEMLKLLD FGSLSNLQVT QPTVGMNFKT PRGPV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards