About Monoacylglycerol lipase ABHD2
Monoacylglycerol lipase ABHD2 (ABHD2) is a protein
from Homo sapiens identified by UniProt accession
P08910, 425 residues long.
MolForge cross-references it against 0 known binders and
144 disease associations.
Target properties
| Protein name | Monoacylglycerol lipase ABHD2 |
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| UniProt accession | P08910 |
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| Gene | ABHD2 |
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| Organism | Homo sapiens |
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| Length | 425 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (144)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.41
- coronary artery disease · score 0.36
- angina pectoris · score 0.36
- myocardial infarction · score 0.33
- phosphatidylcholine measurement · score 0.31
- Vasodilators used in cardiac diseases use measurement · score 0.31
- pulse pressure measurement · score 0.30
- salivary gland disease · score 0.30
- Atrophy · score 0.30
- gut microbiome measurement · score 0.28
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P08910-F1 | alphafold | PREDICTED | 90.97 | — |
Amino-acid sequence (425 residues)
MNAMLETPEL PAVFDGVKLA AVAAVLYVIV RCLNLKSPTA PPDLYFQDSG LSRFLLKSCP LLTKEYIPPL IWGKSGHIQT ALYGKMGRVR SPHPYGHRKF ITMSDGATST FDLFEPLAEH CVGDDITMVI CPGIANHSEK QYIRTFVDYA QKNGYRCAVL NHLGALPNIE LTSPRMFTYG CTWEFGAMVN YIKKTYPLTQ LVVVGFSLGG NIVCKYLGET QANQEKVLCC VSVCQGYSAL RAQETFMQWD QCRRFYNFLM ADNMKKIILS HRQALFGDHV KKPQSLEDTD LSRLYTATSL MQIDDNVMRK FHGYNSLKEY YEEESCMRYL HRIYVPLMLV NAADDPLVHE SLLTIPKSLS EKRENVMFVL PLHGGHLGFF EGSVLFPEPL TWMDKLVVEY ANAICQWERN KLQCSDTEQV EADLE
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