Neuromedin-B (NMB)

About Neuromedin-B

Neuromedin-B (NMB) is a protein from Homo sapiens identified by UniProt accession P08949, 121 residues long. MolForge cross-references it against 0 known binders and 99 disease associations.

Target properties

Protein name	Neuromedin-B
UniProt accession	P08949
Gene	NMB
Organism	Homo sapiens
Length	121 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (99)

Diseases linked to this target (Open Targets).

schizophrenia · score 0.28
bipolar disorder · score 0.26
anorexia nervosa · score 0.24
autism spectrum disorder · score 0.22
dilated cardiomyopathy · score 0.22
aspartate aminotransferase measurement · score 0.20
bipolar I disorder · score 0.20
creatinine measurement · score 0.20
Tourette syndrome · score 0.18
unipolar depression · score 0.18

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P08949-F1	alphafold	PREDICTED	67.93	—

Amino-acid sequence (121 residues)

MARRAGGARM FGSLLLFALL AAGVAPLSWD LPEPRSRASK IRVHSRGNLW ATGHFMGKKS LEPSSPSPLG TAPHTSLRDQ RLQLSHDLLG ILLLKKALGV SLSRPAPQIQ YRRLLVQILQ K

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards