About Homeobox protein Hox-C4
Homeobox protein Hox-C4 (HOXC4) is a protein
from Homo sapiens identified by UniProt accession
P09017, 264 residues long.
MolForge cross-references it against 0 known binders and
314 disease associations.
Target properties
| Protein name | Homeobox protein Hox-C4 |
|---|
| UniProt accession | P09017 |
|---|
| Gene | HOXC4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 264 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (314)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.47
- BMI-adjusted waist circumference · score 0.33
- BMI-adjusted waist-hip ratio · score 0.32
- systolic blood pressure · score 0.32
- platelet count · score 0.32
- smoking behavior · score 0.32
- hypertension · score 0.32
- alcohol drinking · score 0.30
- body fat percentage · score 0.30
- waist-hip ratio · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P09017-F1 | alphafold | PREDICTED | 63.83 | — |
Amino-acid sequence (264 residues)
MIMSSYLMDS NYIDPKFPPC EEYSQNSYIP EHSPEYYGRT RESGFQHHHQ ELYPPPPPRP SYPERQYSCT SLQGPGNSRG HGPAQAGHHH PEKSQSLCEP APLSGASASP SPAPPACSQP APDHPSSAAS KQPIVYPWMK KIHVSTVNPN YNGGEPKRSR TAYTRQQVLE LEKEFHYNRY LTRRRRIEIA HSLCLSERQI KIWFQNRRMK WKKDHRLPNT KVRSAPPAGA APSTLSAATP GTSEDHSQSA TPPEQQRAED ITRL
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