About Fibroblast growth factor 2
Fibroblast growth factor 2 (FGF2) is a protein
from Homo sapiens identified by UniProt accession
P09038, 288 residues long.
MolForge cross-references it against 0 known binders and
1,029 disease associations.
Target properties
| Protein name | Fibroblast growth factor 2 |
|---|
| UniProt accession | P09038 |
|---|
| Gene | FGF2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 288 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (1029)
Diseases linked to this target (Open Targets).
- cancer · score 0.62
- bone development disease · score 0.60
- lean body mass · score 0.55
- female reproductive endometrioid cancer · score 0.50
- ovarian carcinoma · score 0.46
- body height · score 0.43
- sitting height measurement · score 0.43
- whole body water mass · score 0.38
- base metabolic rate measurement · score 0.38
- fat body mass · score 0.38
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P09038-F1 | alphafold | PREDICTED | 70.27 | — |
Amino-acid sequence (288 residues)
MVGVGGGDVE DVTPRPGGCQ ISGRGARGCN GIPGAAAWEA ALPRRRPRRH PSVNPRSRAA GSPRTRGRRT EERPSGSRLG DRGRGRALPG GRLGGRGRGR APERVGGRGR GRGTAAPRAA PAARGSRPGP AGTMAAGSIT TLPALPEDGG SGAFPPGHFK DPKRLYCKNG GFFLRIHPDG RVDGVREKSD PHIKLQLQAE ERGVVSIKGV CANRYLAMKE DGRLLASKCV TDECFFFERL ESNNYNTYRS RKYTSWYVAL KRTGQYKLGS KTGPGQKAIL FLPMSAKS
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