About Homeobox protein Hox-B5
Homeobox protein Hox-B5 (HOXB5) is a protein
from Homo sapiens identified by UniProt accession
P09067, 269 residues long.
MolForge cross-references it against 0 known binders and
133 disease associations.
Target properties
| Protein name | Homeobox protein Hox-B5 |
|---|
| UniProt accession | P09067 |
|---|
| Gene | HOXB5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 269 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (133)
Diseases linked to this target (Open Targets).
- body mass index · score 0.25
- diastolic blood pressure · score 0.14
- grip strength measurement · score 0.11
- hip bone mineral density · score 0.11
- hypertension · score 0.10
- hepatocellular carcinoma · score 0.10
- cardiovascular disease · score 0.10
- systolic blood pressure · score 0.10
- non-small cell lung carcinoma · score 0.09
- fat body mass · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P09067-F1 | alphafold | PREDICTED | 61.11 | — |
Amino-acid sequence (269 residues)
MSSYFVNSFS GRYPNGPDYQ LLNYGSGSSL SGSYRDPAAM HTGSYGYNYN GMDLSVNRSS ASSSHFGAVG ESSRAFPAPA QEPRFRQAAS SCSLSSPESL PCTNGDSHGA KPSASSPSDQ ATSASSSANF TEIDEASASS EPEEAASQLS SPSLARAQPE PMATSTAAPE GQTPQIFPWM RKLHISHDMT GPDGKRARTA YTRYQTLELE KEFHFNRYLT RRRRIEIAHA LCLSERQIKI WFQNRRMKWK KDNKLKSMSL ATAGSAFQP
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