About Hemoglobin subunit theta-1
Hemoglobin subunit theta-1 (HBQ1) is a protein
from Homo sapiens identified by UniProt accession
P09105, 142 residues long.
MolForge cross-references it against 0 known binders and
101 disease associations.
Target properties
| Protein name | Hemoglobin subunit theta-1 |
|---|
| UniProt accession | P09105 |
|---|
| Gene | HBQ1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 142 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (101)
Diseases linked to this target (Open Targets).
- mean corpuscular hemoglobin concentration · score 0.51
- mean corpuscular volume · score 0.48
- mean corpuscular hemoglobin · score 0.48
- Alpha-thalassemia · score 0.47
- alpha thalassemia spectrum · score 0.43
- hemoglobin measurement · score 0.27
- Red cell distribution width · score 0.24
- interstitial lung disease · score 0.24
- reticulocyte count · score 0.21
- reticulocyte measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-P09105-F1 | alphafold | PREDICTED | 96.64 | — |
Amino-acid sequence (142 residues)
MALSAEDRAL VRALWKKLGS NVGVYTTEAL ERTFLAFPAT KTYFSHLDLS PGSSQVRAHG QKVADALSLA VERLDDLPHA LSALSHLHAC QLRVDPASFQ LLGHCLLVTL ARHYPGDFSP ALQASLDKFL SHVISALVSE YR
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