P3 protein (SLC10A3)

About P3 protein

P3 protein (SLC10A3) is a protein from Homo sapiens identified by UniProt accession P09131, 477 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.

Target properties

Protein name	P3 protein
UniProt accession	P09131
Gene	SLC10A3
Organism	Homo sapiens
Length	477 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (30)

Diseases linked to this target (Open Targets).

hemoglobin measurement · score 0.11
mean corpuscular volume · score 0.11
hematocrit · score 0.11
hypertriglyceridemia 2 · score 0.08
cholesterol-ester transfer protein deficiency · score 0.07
Combined hyperlipidemia · score 0.06
thyroid hormone metabolism, abnormal, 2 · score 0.06
sitosterolemia · score 0.05
homozygous familial hypercholesterolemia · score 0.05
neoplasm · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-P09131-F1	alphafold	PREDICTED	76.76	—

Amino-acid sequence (477 residues)

MVLMQDKGSS QQWPGLGGEG GGTGPLSMLR AALLLISLPW GAQGTASTSL STAGGHTVPP TGGRYLSIGD GSVMEFEFPE DSEGIIVISS QYPGQANRTA PGPMLRVTSL DTEVLTIKNV SAITWGGGGG FVVSIHSGLA GLAPLHIQLV DAHEAPPTLI EERRDFCIKV SPAEDTPATL SADLAHFSEN PILYLLLPLI FVNKCSFGCK VELEVLKGLM QSPQPMLLGL LGQFLVMPLY AFLMAKVFML PKALALGLII TCSSPGGGGS YLFSLLLGGD VTLAISMTFL STVAATGFLP LSSAIYSRLL SIHETLHVPI SKILGTLLFI AIPIAVGVLI KSKLPKFSQL LLQVVKPFSF VLLLGGLFLA YRMGVFILAG IRLPIVLVGI TVPLVGLLVG YCLATCLKLP VAQRRTVSIE VGVQNSLLAL AMLQLSLRRL QADYASQAPF IVALSGTSEM LALVIGHFIY SSLFPVP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards